Zyderm® is purified
collagen prepared in a liquid state so that it can be injected into
the skin in order to fill out the wrinkle lines or depressed scars.
This material is almost identical to the collagen in your skin and
so behaves like a graft, the new collagen fibres becoming vascularised
and incorporated into the collagen structure of your skin.
This material has been extensively tested during
the past twenty years. It is most effective for filling out small
contour defects in the skin, for example small-pitted scars, frown
lines or lines around the upper lip and cheeks. It is not suitable
for filling out larger areas, for example in order to build up cheekbones
or chin.
How many injections?
First you require a small test dose in the skin of the forearm to
ensure that you are not allergic to the material (a rare occurrence).
After three weeks, and a negative reaction, the facial skin is injected
and usually requires a second (and occasionally a third) injection
to fully smooth out the wrinkle or depression. These injections
are done through a very fine needle and any slight swelling subsides
within 24 hours. It is better not to use make-up for 24 hours, or
go into strong sunlight.
Occasionally the site of treatment may be slightly
raised, we advise that you massage this area gently with your fingertip.
Is it permanent?
This depends on the type of skin and the, amount of movement. A
small depressed scar is sometimes permanently corrected. A strong
creaseline frequently moving will inevitably recur to a degree over
the 3-4 months, and a "top-up" is then required. Unfortunately
there is no method of making time stand still, but injection of
collagen is more effective and a safer technique than for example
dermabrasion, chemical peel and liquid silicone (this last one I
don’t use), and represents a very real advance in the treatment
of facial wrinkles and small depressed scars.
Restylane®, Perlane® and Newfill®:
In recent years we have been using hyaluronic
acid (Restylane®, Perlane®) and other filler substances
as Newfill®. Each of these types of injectable fillers have
particular advantages for the specific needs of different patients.
Restylane® and Perlane®
are preparations of hyaluronic acid. Restylane® is a lighter
density preparation than Perlane®, this last preparation tends
to provide more solid support and is appropiate in deeper and more
well formed folds than Restylane® which is thinner. Both preparations
are very suitable substances for lip enhancement and for the filling
of skin lines and folds. The occurrence of allergies is less frequent
than for collagen hyaluronic acid treatment that does not require
a test before the treatment.
Restylane® and Perlane® treatments are repeated usually
every 3 to 8 months depending on the rate of re-absorption. Perlane®
lasts longer than Restylane® but usually the tissues temporarily
swell more and very rarely can be visible or palapable.
Newfill® is made
with polylactic acid. This filler is reabsorbable as well but the
filling effects are longer lasting than with hyaluronic acid (12-18
months). Newfill is not suitable for lip enhancement. Newfill®
can be used very successfully for the treatment of deep folds and
facial contouring in the cheek and jaw-line.
All the above filling substances tend to have
specific indications, advantages and disadvantages that should be
balanced in accordance to your specific requirements and complexion.
Side effects and complications are very rare with
the use of re-absorbable fillers but will be discussed in detail
during consultation.
In our office you will also be provided with information
sheets specific for the different products mentioned in these sections.